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Featured Resource:

Orthogonal Polarization Spectral Imaging:
A New Tool for the Observation and Measurement of the Human Microcirculation
Progress in Applied Microcirculation, Vol 24
K. Messmer, Volume Editor
Karger, 1999
ISSN 0254-5195 $100.00 US

Free copy for Cytometrics Website visitors.


Studies Regarding Orthogonal Polarization Spectral Imaging, OPS Imaging

Harris AG, Sinitsina I, Messmer K, "Validation of OPS imaging for microvascular measurements during isovolumic hemodilution and low hematocrits," Am J Physiol Heart Circ Physiol. 2002 Apr 282(4):H1502-9.

Biberthaler P, Langer S, "Comparison of the New OPS Imaging Technique with Intravital Microscopy: Analysis of the Colon Microcirculation," Eur Surg Res. 2002 Jan-Apr 34(1--2):124-8.

Genzel-Boroviczeny O, Strotgen J, Harris AG, Messmer K, Christ F, "Orthogonal polarization spectral imaging (OPS): a novel method to measure the microcirculation in term and preterm infants transcutaneously," Pediatr Res. 2002 Mar 51(3):386-91.

Biberthaler P, Langer S, Luchting B, Khandoga A, Messmer K, "In vivo assessment of colon microcirculation: comparison of the new OPS imaging technique with intravital microscopy," Eur J Med Res. 2001 Dec 17 6(12):525-34.

Vollebregt KC, Boer K, Mathura KR, de Graaff JC, Ubbink DT, Ince C, "Impaired vascular function in women with pre-eclampsia observed with orthogonal polarisation spectral imaging," BJOG. 2001 Nov 108(11):1148-53.

Langer S, Biberthaler P, Harris AG, Steinau HU, Messmer K, "In vivo monitoring of microvessels in skin flaps: introduction of a novel technique," Microsurgery. 2001 21(7):317-24.

Sofola IO, Pazos GA, Buttolph TB, Casler JD, Leonard DW, "The Cytoscan model E-II in intraoperative parathyroid gland identification in a rabbit model," Otolaryngol Head Neck Surg. 2001 Dec 125(6):635-9.

Thomale UW, Schaser KD, Unterberg AW, Stover JF, "Visualization of rat pial microcirculation using the novel orthogonal polarized spectral (OPS) imaging after brain injury," J Neurosci Methods. 2001 Jul 15 108(1):85-90.

Boros M, "[Methods for in vivo investigation of human microcirculation]" Orv Hetil. 2001 May 27 142(21):1111-4. Hungarian.

De Backer D, Dubois MJ, "Assessment of the microcirculatory flow in patients in the intensive care unit," Curr Opin Crit Care. 2001 Jun 7(3):200-3. Review.

Langer S, Hatz R, Harris AG, Hernandez-Richter T, Maiwald G, Messmer K, "Assessing the microcirculation in a burn wound by use of OPS imaging, ' Eur J Med Res. 2001 Jun 28 6(6):231-4.

Mathura KR, Vollebregt KC, Boer K, De Graaff JC, Ubbink DT, Ince C, "Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation," J Appl Physiol. 2001 Jul 91(1):74-8.

Tugtekin IF, Radermacher P, Theisen M, Matejovic M, Stehr A, Ploner F, Matura K, Ince C, Georgieff M, Trager K, "Increased ileal-mucosal-arterial PCO2 gap is associated with impaired villus microcirculation in endotoxic pigs," Intensive Care Med. 2001 Apr 27(4):757-66.

Langer S, Harris AG, Biberthaler P, von Dobschuetz E, Messmer K, "Orthogonal polarization spectral imaging as a tool for the assessment of hepatic microcirculation: a validation study," Transplantation. 2001 May 15 71(9):1249-56.

Nadeau RG, Groner W, "The role of a new noninvasive imaging technology in the diagnosis of anemia," J Nutr. 2001 May 131(5):1610S-4S.

Harris AG, Sinitsina I, Messmer K, "The Cytoscan Model E-II, a new reflectance microscope for intravital microscopy: comparison with the standard fluorescence Method," J Vasc Res. 2000 Nov-Dec 37(6):469-76.

Menger MD, Vollmar B, "Role of microcirculation in transplantation," Microcirculation. 2000 Oct 7(5):291-306. Review.

Groner W, Winkelman JW, Harris AG, Ince C, Bouma GJ, Messmer K, Nadeau RG, "Orthogonal polarization spectral imaging: a new method for study of the microcirculation," Nat Med. 1999 Oct 5(10):1209-12.

Boehm, D. H., F. Christ, A. G. Harris, H. Reichenspurner, B. Reichert and K. Messmer. (2000) First application of intravital microscopy on the beating heart using OPS imaging. J. Vasc. Res., 37 (Suppl. 1): 23. (Abstract) Selected poster

Gaughan, R. (2000) Bloodless blood counts, in a matter of seconds. Biophotonics International, 7:4, 26.

Groner, W., J. W. Winkelman, A. G. Harris, C. Ince, G. J. Bouma, K. Messmer and R. G. Nadeau. (1999) Orthogonal polarization spectral imaging: A new method for the study of the microcirculation. Nature Medicine 5: 6-10.

Harris, A. G., S. Langer and K. Messmer. (2000) The study of the microcirculation using orthogonal polarization spectral imaging. In Yearbook of Intensive Care and Emergency Medicine 2000, Editor J.-L. Vincent, Springer-Verlag, Berlin, pp 705-14.

Harris, A., S. Pahernik, I. Sinitsina, K. Messmer. (2000) Orthogonal Polarization Spectral Imaging for the Quantification of Microvascular Parameters. J. Vasc. Res., 37:305-341. (Abstract)

Harris, A. G., S. Pahernik, I. Sinitsina, S. Langer and K. Messmer. (2000) Results from OPS validation experiments. Shock, 13 (Suppl. 1): 65. (Abstract).

Harris, A. G., S. Pahernik, I. Sinitsina and K. Messmer. (2000) Validation of OPS imaging. 21st European Conference on Microcirculation. Editor: B. Fagrell. Bologna: Monduzzi Editore, pp. 43-48.

Harris, A. G., S. Pahernik, I. Sinitsina and K. Messmer. (2000) Validation of orthogonal polarization spectral (OPS) imaging for quantitative microvascular measurements in the hamster dorsal skinfold chamber. J. Vasc. Res., 37 (Suppl. 1): 22. (Abstract)

Harris, A. G., I. Sinitsina and K. Messmer. (2000) Validation of the CYTOSCAN A/R for intravital measurements in the microcirculation of the hamster dorsal skinfold chamber. FASEB J. 14: A16. (Abstract).

Harris, A. G., I. Sinitsina and K. Messmer. (2000) Validation of OPS imaging for microvascular measurements in the hamster dorsal skinfold chamber. Pflügers Arch. 439 (6, Suppl.) : R385. (Abstract).

Harris, A. G., I. Sinitsina and K. Messmer. (1999) Validation of the orthogonal polarization spectral (OPS) imaging system for intravital measurements in the microcirculation. Anesthesiology 91 (Suppl. 1): A641 (Abstract).

Langer, S., A. G. Harris, P. Biberthaler, F. Krombach and K. Messmer. (2000) Validation of the OPS imaging technique in the rat liver. Langenbecks Arch.Chir. Suppl. Kongressbd. 117: 309-312.

Langer, S., F. Born, A. G. Harris, E. Uhl and K. Messmer. (2000) Visualization of skin microcirculation using OPS imaging. J. Vasc. Res., 37 (Suppl. 1): 22. (Abstract)

Nadeau, R. G. (2000) The Technique of Orthogonal Polarization Spectral (OPS) Imaging. Shock, 13 (Suppl. 1): 65. (Abstract).

Schaudig, S., M. Niklas, C. Schiessler, A. G. Harris, H. C. Reichenspurner, S. Eiffert, K. Messmer and F. Christ. (2000) Intravital microscopy in humans during cardiac surgery. J. Vasc. Res., 37 (Suppl. 1): 10. (Abstract)

Siegemund, M., J. van Bommel, C. Ince. (1999) Assessment of regional tissue oxygenation. Intensive Care Med, 25: 1044-1060.

Winkelman, J.W. (2000) Noninvasive Blood Cell Measurements by Imaging of the Microcirculation. AJCP, 4: Special Article

Uehling, M. Under the skin: sorting through the hype and hope for noninvasive POC devices (2000) CAP Today, 14.7: 52-68.

Uhl, E., Lehmberg, J., Steiger, H. J., Messmer, K. (2000) OPS In Neurosurgery. Shock, 13 (Suppl. 1): 65. (Abstract).